118 lines
3 KiB
R
118 lines
3 KiB
R
rm(list = ls(all.names = TRUE)) # Clear the memory of variables from previous run.
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cat("\014") # Clear the console
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# load packages -----------------------------------------------------------
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box::use(
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magrittr[`%>%`]
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,RSQLite
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,DBI[dbConnect,dbDisconnect]
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,here[here]
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,dplyr
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,dbplyr
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,tidyr
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,readr
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)
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# globals -----------------------------------------------------------------
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db <- dbConnect(
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RSQLite$SQLite()
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,here("ML","data-unshared","mimicDB.sqlite")
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)
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#item list shows two different numbers for a few tests, second set of items do not have
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# any results that are on the same samples as TSH and Free T4
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# 51301 and 51300 looks like test name may have changed
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test_list_bmp <- c(
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51006 #Urea Nitrogen
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,50893 #Calcium, Total
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,50882 #Bicarbonate
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,50902 #Chloride
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,50912 #Creatinine
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,50931 #Glucose
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,50971 #Potassium
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,50983 #Sodium
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,50993 #Thyroid Stimulating Hormone
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,50995 #Thyroxine (T4), Free
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,51279 #RBC
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,51301 #White Blood Cells
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,51300 #WBC Count
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,51221 #Hematocrit
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,51222 #Hemoglobin
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,51265 #Platelet Count
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)
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test_list_names <- c(
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"BUN" = "51006"
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,"CA" = "50893"
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,"CO2" = "50882"
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,"CL" = "50902"
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,"CREA" = "50912"
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,"GLU" = "50931"
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,"K" = "50971"
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,"NA" = "50983"
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,"TSH" = "50993"
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,"FT4" = "50995"
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,"RBC" = "51279"
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,"WBC" = "51300"
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,"HCT" = "51221"
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,"HGB" = "51222"
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,"PLT" = "51265"
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)
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# TSH Ref Range from File 0.27 - 4.2 uIU/mL
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# Free T4 Ref Range from File 0.93 - 1.7 ng/dL
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# load data ---------------------------------------------------------------
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# load patients first to add to lab values
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patients <- dplyr$tbl(db, "patients") %>%
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dplyr$select(-anchor_year, -anchor_year_group, -dod) %>%
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dplyr$collect()
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# usable data set is using chart time as it appears
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# LIS uses different id's for groups of tests
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# BMP and CBC Results together
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ds_bmp <- dplyr$tbl(db, "labevents") %>%
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dplyr$filter(itemid %in% test_list_bmp) %>%
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dplyr$select(-storetime) %>%
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tidyr$pivot_wider(
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id_cols = c(subject_id,charttime)
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,names_from = itemid
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,values_from = valuenum
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) %>%
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dplyr$collect()
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ds1 <- ds_bmp %>%
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dplyr$filter(!is.na(`50993`) & !is.na(`50995`)) %>%
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dplyr$left_join(patients, by = c("subject_id" = "subject_id")) %>%
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dplyr$mutate(dplyr$across(`51300`, ~dplyr$if_else(!is.na(.),`51300`,`51301`))) %>%
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dplyr$select(-`51301`) %>%
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# dplyr$filter(dplyr$if_all(.fns = ~!is.na(.)))
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dplyr$filter(rowSums(is.na(.)) <= 3) #allows for 3 missing test
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ds_final <- ds1 %>%
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dplyr$mutate(
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ft4_dia = dplyr$case_when(
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`50993` > 4.2 & `50995` < 0.93 ~ "Hypo"
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,`50993` > 4.2 & `50995` > 0.93 ~ "Non-Hypo"
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,`50993` < 0.27 & `50995` > 1.7 ~ "Hyper"
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,`50993` < 0.27 & `50995` < 1.7 ~ "Non-Hyper"
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,TRUE ~ "Normal TSH"
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)
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) %>%
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dplyr$rename(!!!test_list_names) %>%
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dplyr$relocate(gender, anchor_age)
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# save data ---------------------------------------------------------------
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ds_final %>% readr$write_rds(here("ML","data-unshared","ds_final.RDS"))
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# close database ----------------------------------------------------------
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dbDisconnect(db)
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