# Methods

need brief description and IRB statement

## Population and Data

This study was designed using the Medical Information Mart for Intensive
Care (MIMIC) database [@johnsonalistair]. MIMIC (Medical Information
Mart for Intensive Care) is an extensive, freely-available database
comprising de-identified health-related data from patients who were
admitted to the critical care units of the Beth Israel Deaconess Medical
Center. The study uses version IV of the database, containing data from
2008 - 2019. The database contains many different types of information,
but only data from the patients and laboratory events table are used in
this study.

## Data Variables and Outcomes

A total of 18 variables were chosen for this study. The age and gender
of the patient were pulled from the patient table in the MIMIC database.
While this database contains some additional demographic information, it
is incomplete and thus unusable for this study. 16 lab values were
selected for this study, this includes:

-   **BMP**: BUN, bicarbonate, calcium, chloride, creatinine, glucose,
    potassium, sodium

-   **CBC**: Hematocrit, hemoglobin, platelet count, red blood cell
    count, white blood cell count

-   TSH

-   Free T4

## Data Transformations

In progress