Update 1-data-exploration.R
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1 changed files with 31 additions and 81 deletions
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@ -17,36 +17,11 @@ box::use(
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# globals -----------------------------------------------------------------
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test_list_names <- c(
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"BUN" = "51006"
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,"CA" = "50893"
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,"CO2" = "50882"
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,"CL" = "50902"
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,"CREA" = "50912"
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,"GLU" = "50931"
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,"K" = "50971"
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,"NA" = "50983"
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,"TSH" = "50993"
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,"FT4" = "50995"
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,"RBC" = "51279"
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,"WBC" = "51300"
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,"HCT" = "51221"
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,"HGB" = "51222"
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,"PLT" = "51265"
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)
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# load data ---------------------------------------------------------------
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ds_high_tsh_raw <- readr$read_rds(
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here("ML","data-unshared","ds_high_tsh.RDS")
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)
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ds_low_tsh_raw <- readr$read_rds(
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here("ML","data-unshared","ds_low_tsh.RDS")
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)
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ds0 <- readr$read_rds(here("ML","data-unshared","ds_final.RDS"))
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# data manipulation -------------------------------------------------------
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@ -54,69 +29,44 @@ ds_low_tsh_raw <- readr$read_rds(
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# using the FT4 Referance range low as the cut off (0.93)
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ds_high_tsh <- ds_high_tsh_raw %>%
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dplyr$mutate(ft4_dia = dplyr$if_else(`50995` < 0.93, TRUE, FALSE)) %>%
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#can rename with a vector using either of these
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# dplyr$rename_with(~names(test_list_names), dplyr$all_of(test_list_names))
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dplyr$rename(!!!test_list_names) %>%
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ds1 <- ds0 %>%
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dplyr$select(-FT4, -subject_id, -charttime) %>%
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dplyr$relocate(gender, anchor_age)
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ds_low_tsh <- ds_low_tsh_raw %>%
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dplyr$mutate(ft4_dia = dplyr$if_else(`50995` > 1.7, TRUE, FALSE)) %>%
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#can rename with a vector using either of these
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# dplyr$rename_with(~names(test_list_names), dplyr$all_of(test_list_names))
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dplyr$rename(!!!test_list_names) %>%
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dplyr$select(-FT4, -subject_id, -charttime) %>%
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dplyr$relocate(gender, anchor_age)
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dplyr$mutate(dplyr$across(
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ft4_dia
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, ~factor(., levels = c("Hypo", "Non-Hypo", "Normal TSH", "Hyper", "Non-Hyper")
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)
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)
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)
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# basic visualization -----------------------------------------------------
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#summary Table
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#use this instead of making myself
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summary_table <- function(ds){
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table <- ds %>%
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gtsummary$tbl_summary(
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by = ft4_dia
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,missing = "no"
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,type = gtsummary$all_continuous() ~ "continuous2"
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,label = list(
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gender ~ "Gender"
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,anchor_age ~ "Age"
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)
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,statistic = gtsummary$all_continuous() ~ c(
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"{N_miss}"
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,"{median} ({p25}, {p75})"
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,"{min}, {max}"
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)
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) %>%
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gtsummary$bold_labels() %>%
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gtsummary$add_stat_label(
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label = gtsummary$all_continuous() ~ c("Missing", "Median (IQR)", "Range")
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) %>%
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gtsummary$modify_header(label = "**Variable**") %>%
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gtsummary$modify_spanning_header(gtsummary$all_stat_cols() ~ "**Free T4 Diagnostic**")
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return(table)
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}
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# create both tables
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high_table_summary <- summary_table(ds_high_tsh)
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low_table_summary <- summary_table(ds_low_tsh)
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# merge tables
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merged_summary_table <- gtsummary$tbl_merge(
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tbls = list(high_table_summary, low_table_summary)
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,tab_spanner = c(
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"**Elevated TSH** \n Free T4 Diagnostic"
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,"**Decreased TSH** \n Free T4 Diagnostic"
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)
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summary_tbl <- ds1 %>%
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gtsummary$tbl_summary(
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by = ft4_dia
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,missing = "no"
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,type = gtsummary$all_continuous() ~ "continuous2"
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,label = list(
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gender ~ "Gender"
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,anchor_age ~ "Age"
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)
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,statistic = gtsummary$all_continuous() ~ c(
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"{N_miss}"
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,"{median} ({p25}, {p75})"
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,"{min}, {max}"
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)
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) %>%
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gtsummary$bold_labels() %>%
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gtsummary$add_stat_label(
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label = gtsummary$all_continuous() ~ c("Missing", "Median (IQR)", "Range")
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) %>%
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gtsummary$as_flex_table()
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gtsummary$modify_header(label = "**Variable**") %>%
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gtsummary$modify_spanning_header(gtsummary$all_stat_cols() ~ "**Free T4 Diagnostic**")
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# summary_tbl
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# correlation plot
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