2022-08-03 10:40:23 -04:00
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# Introduction
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2022-08-21 14:24:50 -04:00
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The primary business purpose of the clinical laboratory is to provide
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results of testing requested by physicians and other healthcare
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professionals. This testing in a broad sense is used to help solve
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diagnostic problems [@verboeket-vandevenne2012]. To continue to add
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value to the business purpose of the laboratory, laboratory
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professionals can add value beyond just running the provided tests.
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Laboratory professionals can add value through both reflective and
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reflex testing. Automated analyzers add most tests based on rules
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(algorithms) established by laboratory professionals; this is defined as
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'reflex testing.' Clinical biochemists add the remainder of tests after
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considering a more comprehensive range of information than can readily
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be incorporated into reflex testing algorithms; this is defined as
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'reflective testing' [@srivastava2010]. Both reflex and reflective
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testing became possible with the advent of laboratory information
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systems (LIS) that were sufficiently flexible to permit modification of
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existing test requests at various stages of the analytical process
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[@srivastava2010]. This research study will focus specifically on reflex
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testing, those tests added automatically by a set of rules established
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in each laboratory. In most current clinical laboratories, reflex
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testing is performed with a 'hard' cutoff, using a specifically
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established range with no means of flexibility [@murphy2021].
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<!--# Rewrite this section -->
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This study will examine the use of Machine learning to develop
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algorithms to allow flexibility for automatic reflex testing in clinical
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chemistry. The goal is to fill the gap between hard coded reflex testing
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and fully manual reflective testing using machine learning algorithms.
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<!--# -->
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## Statement of Problem
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## Purpose and Research Question
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### Draft Question
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What are the beliefs, attitudes, opinions, and knowledge about machine
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learning in the clinical laboratory.
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## Significance
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